Within the UPMC Center for Skull Base Surgery, Dr. Choby, Dr. Wang, and Dr. Snyderman are dedicated to advancing the treatment of sinonasal malignancies. Active areas of research include improving survival in patients with sinonasal cancers, understanding the role of induction chemotherapy in the treatment of advanced-stage tumors, and improving quality of life outcomes following therapy. Highlights of ongoing studies include proliferative and immunologic profiling of sinonasal mucosal melanoma and helping to lead a multi-site consortium prospectively evaluating survival outcomes and tissue banking of sinonasal malignancies. Several other multi-center studies dedicated to understanding the biologic behavior of olfactory neuroblastoma (esthesioneuroblastoma) are also underway.
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