Department of Otolaryngology

Stella Lee, MD

  • Assistant Professor, Department of Otolaryngology
  • Director, Division of Sino-nasal Disorders and Allergy

Education & Training

  • Yale University in New Haven, CT 2010, Otolaryngology Residency Training
  • Johns Hopkins University in Baltimore, Maryland- Fellowship training in Rhinology and Skull Base Surgery

Representative Publications

Orlandi RR, Kingdom TT, Hwang PH et al. contributing author Lee S. Int Forum Allergy Rhinol. International Consensus Statement on Allergy and Rhinology: Rhinosinusitis. 2016 Feb;6 Suppl 1:S22-S209.

Rowan NR, Lee S, Sahu N, Kanaan A, Cox S, Phillips CD, Wang EW. The role of viruses in the clinical presentation of chronic rhinosinusitis. Am J Rhinol Allergy. 2015 Nov;29(6):197-200.

Leatherman BD, Khalid A, Lee S, McMains K, Peltier J, Platt MP, Stachler RJ, Toskala E, Tropper G, Venkatraman G, Lin SY. Dosing of sublingual immunotherapy for allergic rhinitis: evidence-based review with recommendations. Int Forum Allergy Rhinol. 2015 Sep;5(9):773-83.

Hobson CE, Choby GW, Wang EW, Morton SC, Lee S. Systematic review and meta-analysis of middle meatal packing after endoscopic sinus surgery. Am J Rhinol Allergy. 2015 Mar-Apr;29(2):135-40.

Mattos JL, Ferguson BJ, Lee S. Impact of quality improvement measures on the delivery of allergy immunotherapy:  A 2-year follow-up. Int Forum Allergy Rhinol. 2015 Jun;5(6):513-6. 

View Dr. Lee's most current publications.

Research Interest Summary

Sinonasal Microbiome, Role of viruses in the propagation and survival of bacterial biofilm in patients with cystic fibrosis, Environmental factors in the development of upper airway inflammation & chronic rhinosinusitis

Research Interests

Dr. Lee's current research projects involve:

  • The effects of antimicrobial therapy and functional endoscopic sinus surgery on the paranasal sinus microbiome composition of patients with chronic rhinosinusitis

  • The mechanisms of iron modulation in virally-induced biofilm production in patients with chronic rhinosinusitis and cystic fibrosis

  • Mapping patients with chronic rhinosinusitis by severity to air quality in Western PA to determine affects of small and large airborne particulates in chronic airway inflammation

  • The efficacy of topical antimicrobials in patients with chronic bacterial rhinosinusitis

  • Efficacy of clinical trials utilizing monoclonal antibody therapies to target inflammatory pathways in mast cells and eosinophils

Research Grants

2016-present, A Phase 2, randomized, double-blind, placebo controlled study to evaluate multiple doses of AK001 in patients with moderate to severe nasal polyposis, Sponsor:  Allakos, Inc.

2014-present, Viral infection and biofilm induction in cystic fibrosis patients with chronic rhinosinusitis, Sponsor:  University of Pittsburgh Clinical and Translational Science Institute (CTSI) Basic to Clinical Collaborative Research Pilot Program

2014-present, Safety and preliminary efficacy of dexpramipexole in patients with chronic rhinosinusitis with nasal polyps and eosinophilia, Sponsor: Knopp Biosciences

2013-2015, A randomized, double-blind, phase 2, placebo controlled, 2 arm study to evaluate Dupilumab in patients with bilateral nasal polyposis and chronic symptoms of sinusitis, Sponsor: Sanofi Aventis